Top 10 hospital information system vendors in 2025: Custom vs OTS

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Most common hospital information system (HIS) vendors that you can find provide either off-the-shelf (OTS) or custom-made solutions. OTS products are cheap, commonly available, equipped with basic functions, but there is not enough room for modification. On the other hand, tailor-made hospital information system solutions can be easily modified according to client’s requirements, yet the price is essentially higher than its counterpart. In this post, we shall discover both types of vendors, look at the top 10 hospital information system companies, and weigh the pros and cons of each approach.

Top 5 customized HIS vendors to work with

If you are looking for someone to build a HIS from scratch or customize it from a pre-built solution, this list is for you. Here is the review of the top 5 leaders, including their offer, outsourcing model, talent pool, and many more.

1. Synodus

As the leading hospital information system vendors for APAC, Synodus have served 30+ healthcare facilities and 10,000+ healthcare staff.  

Synodus’s team

We are specialized in using IoT, Data analytics, AI and Blockchain to transform your healthcare facility with automation and intelligent tools. Alongside an extensive tech stack and flexible development method, we ensure a seamless HIS deployment with quality code. 

Comply with HIPAA, HL7, ISO and local regulation, we offer both legal expert and 250+ well-versed developers for your HIS. Thanks to our HIS, our clients have recorded: 

  • A 300% revenue boost 
  • Digitize 80% to 90% of paperwork 
  • Satisfaction level increased by an average 30% 

Having 5 stars rating on Clutch and 88% client satisfaction, we promise an instant support, straightforward communication, and detailed-oriented execution, just what our clients adored the most! 

Here’s what you will get working with Synodus – the top hospital information system company:  

  • Main HIS features: EMR/EHR, LIS, RIS, Inventory management for medicine and equipment, Pharmacy management, Insurance and billing, Appointment scheduling, Telehealth, Mobile app for patients, Report and analytics, HRM, CRM, ERP;
  • Number of staff: 250+; 
  • Outsourcing services: Packaged HIS solutions, Customized HIS solution, Staff augmentation, Project-based.
  • Hourly rate: $25 – $50 per hour

2. Comarch

Aiming to deliver a revolutionary approach to healthcare, Comarch is an accomplished international company trusted by facilities worldwide. The hospital information system vendor has been providing tailored solutions for clinics, large hospitals, medical facilities, remote diagnosis, cardiac care, laboratories, and physicians.   

What makes Comarch stand out is their use of AI and machine learning to create HIS, providing the highest quality healthcare systems. 

  • Main HIS features: Administrative processes, patient data management, streamlining patient treatment, finance & billing, and healthcare documentation;   
  • Number of staff: >1000; 
  • Outsourcing services: Packaged HIS solutions, Customized HIS solution; 
  • Compliance standards: HL7CDA, IHE profiles (CDS.b, XCA); 
  • Achievements: Comarch is currently providing HIS support for 80 hospitals, 200 outpatient clinics, and 2.5M annual patients.
  • Hourly rate: $50 – $100 per hour

3. TCA

TCA Healthcare has been working for 40 years to develop secure and effective healthcare ecosystems. This HIS company harnesses the power of innovation and ease-of-use, utilizing it to support both patients and the healthcare system throughout every stage of clinical and medical processes.   

TCA hospital information system offers solutions for healthcare centers, hospitals, and clinics in the public and private sectors. They aim to improve operational effectiveness and increase financial and administrative performance.   

  • Main HIS features: Administrative management, EHR/EMR, Patient portal, Telemedicine, Financials & administration, Reports & analytics;
  • Number of staff: <300; 
  • Outsourcing services: Packaged and custom solutions, IT staff augmentation for HIS support and maintenance, Health IT consulting;    
  • Achievements: 30,000 healthcare users, 2,000 successful implementation and consultation. 
  • Hourly rate: $50 per hour 

4. Chetu

Chetu – Enhancing healthcare through cutting-edge AI-powered solutions

Another prominent customized hospital information system vendor is Chetu. Much like Comarch, the team is known for using deep learning and artificial neural networks to build a comprehensive HIS. It gives real-time patient updates and improves the quality of care at a lower cost.   

Customers can also contact Chetu for various healthcare app development, AI-powered solution, and software applications that are innovative and compliant with regulatory standards. 

  • Main HIS features: Automating administration tasks, Finance and insurance management, EHR/ EMR, Billing management, Inventory management;
  • Number of staff: >2,800;
  • Outsourcing services: Packaged solutions, Staff augmentation;
  • Compliance standard: HL7, ICD-10, CPT, LOINC, SNOMED – CT, Clinical Quality Measure (CQM) tracking. 
  • Hourly rate: $50 per hour 

5. Fortunesoft

Promised to deliver quality, this hospital information system company utilizes many emerging technologies and approaches, namely DevOps, Cloud, CI/CD, and AI. Thanks to this, Fortunesoft quickly gained the heart of many facilities, serving healthcare facilities, hospitals and clinic chains.  

Working with Fortunesoft, you gain access to an agile development approach, high-end security, enhanced management, and incessant support at an affordable price and less chance of errors.   

  • Main support features: Appointment scheduling, Outpatient management, Reporting and analytic dashboards, Prescription management, Registration management, EHR/EMR;
  • Outsourcing services: Project-based outsourcing, Staff augmentation.
  • Hourly rate: $50 per hour 

Pros & cons of customized hospital information system

It takes effort and consideration when choosing a custom HIS partner

Customizing a hospital information system surely takes time and resources, but why do many healthcare providers still choose this route? 

  • You can design an HIS that meets the unique workflow of your facility. This scalable and adaptive system matches all your requirements and the facility’s needs.  
  • You can flexibly integrate new technologies, existing systems, equipment, and third-party applications.  
  • A good HIS should serve local patients and doctors, or localization, for short. By tailoring it, you can freely adjust the system to adhere to global and regional standards, making it more reliable in dealing with sensitive patient data. 

However, it’s not always a pot of gold. You must prepare to spend resources on development. It takes longer to design, test, implement, maintain, and update than using OTS. 

Another constraint is the lack of IT talent in healthcare facilities to build and manage HIS. One way to escape this is hiring a HIS development company like our list above, which can save you money on HRM management and recruitment.  

Yet, it also comes with the questions of choosing the right vendor, identifying red flags, and managing your outsourced team (which we will talk about later). If you fail to do this, the cost is much higher than the development of your HIS. Switching to another health information system vendors mid-plan can be challenging and costly. 

Need experienced & cost-effective healthtech developers?

Customized software is best for: 

  • Mid-size to large healthcare facility. 
  • If you want to implement complex technology such as AI, data analytics, blockchain, or advanced IoT into your HIS.

Top 5 HIS software providers to buy from

For off-the-shelf HIS, which vendors are currently the top of the market? How can they stand out and are trusted by many clients? Here are our top 5.  

1. Epic

Epic HIS provider
Epic system helps people get well and future generation be healthier

Epic is a well-known American healthcare software provider, also known as “Epic EHR.” At first, Epic mainly provided electronic medical record (EMR) solutions. Later, they expand their offer with more and more healthcare software for patient-facing operations, for doctors, and for specialized departments. From that list, you can pick out what you need and assemble an HIS of your own, thanks to flexible API integration. 

Epic is applied and used by many medical schools and US News & World Report’s top-ranked hospitals. Since 2015, Epic has been adopted in several billion-dollar projects.   

  • Notable features: Patient data management with EHR/EMR, Finance and billing management, Healthcare analytics, Digital patient experience, Inpatient management, Remote care.  

2. Oracle

Oracle HIS provider
Oracle Health attempts to reimagine future of healthcare

Being known worldwide as the top software provider, Oracle also marks their name as a leading competitive hospital information system vendor. Here’s why. When creating their HIS, it’s surrounded by intelligent tools, bringing a data-driven and human-centric mindset. 

Partners of Oracle can find products that suit them the most, whether it is about clinical, financial or operational solutions. Some of the HIS company’s applications are Oracle Health EHR, Oracle Health Outpatient Pharmacy, Reference Lab Network, and AmeraCare Long-Term Care Revenue Cycle. 

  • Compliance standard: Corporate security practices, Oracle software security assurance, Oracle cloud security practices, and HIPAA.   

3. Veradigm

Veradigm, formerly known as Allscripts, is another top-of-the-game hospital information system provider of easy-to-use solutions. The HIS vendor delivers actionable insights to clients to drive improved outcomes and a better understanding of patients’ health and medication.  

You can request Veradigm products and services in Practice Management, Revenue Cycle Management, EHR, and Patient Engagement. Using Veradigm’s solutions, clients can lessen the administration burden, improve financial performance, cut costs and waiting times to boost patient satisfaction, and supply patients with their medication on time.   

4. Athenahealth

Hospital information system vendor Athenahealth is a private company specializing in network-enabled healthcare services and point-of-care mobile apps. Athenahealth offers EHR, RCM, and patient engagement solutions so that healthcare workers can fully focus on their patients, lessen risk, increase revenue, and gain real-time insight for more informed decisions.   

Each client has unique needs and goals, and Athenahealth can tailor distinctive experiences for those needs with additional services. 

  • Compliance standard: Common security framework, Payment card industry – Data security standard, Electronic prescriptions for controlled substances, Electronic healthcare network accreditation commission, and many more.    

5. Trubridge

Trubridge, formerly known as CPSI, is a community-oriented hospital information system vendor. They recognize the necessity of quality healthcare and attempt to support healthcare providers in delivering best patient care.  

The HIS vendor offers a range of innovative products and collaborative tools to help their clients overcome financial and operational obstacles. Trubridge’s notable products include Patient Access, 3R Management Suite, and AR Recovery Workdown.   

  • Compliance standard: ONC certification criteria for health IT ( CHBase CEHRT Edition 20, InstantPHR CEHRT edition 20. 

Pros & cons of using off-the-shelf hospital information system

It takes effort and consideration when choosing an OTS product

Off-the-shelf HIS are affordable and instantly available. They’re made for commercial use and are always ready to deploy, well-tested, stable, and reliable. Because of that, implementation requires less time and resources than custom solutions.  

Also, most hospital information system vendors offer comprehensive support and training materials, allowing staff to learn and use these HISs more effectively.   

On the other hand, off-the-shelf HIS solutions don’t have much room for customization, thus not fulfilling specific needs. They might not scale effectively with the growth of your healthcare facility. These HISs also include unnecessary features, adding complexity and potential overhead.  

Also, organizations may develop dependency on vendor for updates, support, and modifications, which can be a risk once the vendor’s service quality declines or if they go out of business.  

If you choose a new off-the-shelf system, migrating data can be complex and time-consuming. While ready-made solutions often have robust security measures, they might not address specific security requirements unique to a particular healthcare facility. 

Off-the-shelf HIS is best for: 

  • Small to mid-size healthcare facility. 
  • When you lack resources, finance and IT specialists to build a HIS.  
  • When your facility only requires a simple HIS to boost internal performance short-term.  

What to consider when choosing your hospital information system vendor

Now that you have a list of potential hospital information system vendors, bear in mind these criteria to pick out the golden one: 

  • A plus if their ideal customer profiles or they’ve already served clients with the same facility size and HIS requirements as yours. Ask for their portfolio to check this.  
  • What are their main features? Are they open to third-party integration and to what extent? How good are they with scalability? These questions are required for off-the-shelf HIS.  
  • Do they adhere to any security standards? How do they secure your patient data? Do those security standards meet your regional standards as well?  
  • Next, will your HIS comply with regional regulatory on healthcare and the use of technology for healthcare? If you are hiring a hospital information system development company, find someone that understands your regional law and culture.  
  • Check to make sure your HIS has a friendly interface and is easy to use. Keep in mind that it will serve users of all demographics.  
  • Make sure your vendor provides training, maintenance and support after deployment.  

Wrapping up

In conclusion, choosing the right hospital information system vendors is a critical decision that can impact the efficiency and quality of healthcare delivery. Whether opting for an off-the-shelf solution or a tailored custom system, you should weigh the pros and cons of each approach. By thoroughly assessing these aspects and aligning them with your facility’s goals, you can make an informed decision that enhances operational efficiency, ensures data security, and improves patient care. 

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